Monday, May 20, 2013

greenhouse effect

The greenhouse effect is a process by which thermal radiation from a planetary surface is absorbed by atmospheric greenhouse gases, and is re-radiated in all directions. Since part of this re-radiation is back towards the surface and the lower atmosphere, it results in an elevation of the average surface temperature above what it would be in the absence of the gases.

Solar radiation at the frequencies of visible light largely passes through the atmosphere to warm the planetary surface, which then emits this energy at the lower frequencies of infrared thermal radiation. Infrared radiation is absorbed by greenhouse gases, which in turn re-radiate much of the energy to the surface and lower atmosphere. The mechanism is named after the effect of solar radiation passing through glass and warming a greenhouse, but the way it retains heat is fundamentally different as a greenhouse works by reducing air flow, isolating the warm air inside the structure so that heat is not lost by convection.

If an ideal thermally conductive blackbody was the same distance from the sun as the Earth is, it would have a temperature of about 5.3 °C. However, since the Earth reflects about 30% of the incoming sunlight, this idealized planet's effective temperature (the temperature of a black body that would emit the same amount of radiation) would be about -18 °C. the surface temperature of this hypothetical planet is 33 °C below the Earth's actual surface temperature of approximately 14 °C. The mechanism that produces this difference between the actual surface temperature and the effective temperature is due to the atmosphere and is known as the greenhouse effect.

Earth's natural greenhouse effect makes life as we know it possible. However, human activities, primarily the burning of fossil fuels and clearing of forests, have intensified the natural greenhouse effect, causing global warming.

By their percentage contribution to the greenhouse effect on Earth, the four major gases are:
  • water vapor, 36-70%
  • carbon dioxide, 9-26%
  • methane, 4-9%
  • ozone, 3-7%

Greenhouse gas
A greenhouse (sometimes abbreviated GHG) is a gas in an atmosphere that absorbs and emits radiation within the thermal infrared range. This process is the fundamental cause of the greenhouse effect. The primary greenhouse gases in the Earth's atmosphere are water vapor, carbon dioxide, methane, nitrous oxide, and ozone. Greenhouse gases greatly affect the temperature of the Earth; without them, the Earth's surface would average about 33 °C colder than the present average of 14 °C (57 °F).

Since the beginning of the Industrial Revolution, the burning of fossil fuels has contributed to a 40% increase in the concentration of carbon dioxide in the atmosphere from 280ppm to 397ppm, despite the uptake of a large portion of the emissions by various natural "sinks" involved in the carbon cycle. Anthropogenic carbon dioxide (CO²) emissions (i.e., emissions produced by human activities) come from combustion of carbon-based fuels, principally wood, coal, oil, and natural gas.

Greenhouse
A greenhouse is a structural building with different types of covering materials that pass sunlight, usually glass, or plastic. It mainly heats up because the sun warms the ground inside, which then warms the air in the greenhouse. The air continues to heat because it is confined within the greenhouse, unlike the environment outside the greenhouse where warm air near the surface rises and mixes with cooler air aloft. In addition, the warmed structures and plants inside the greenhouse re-radiate some of their thermal energy in the infrared spectrum, to which glass is partly opaque, so some of this energy is also trapped inside the greenhouse. However, this latter process is a minor player compared with the former (convective) process. Thus, the primary heating mechanism of a greenhouse is convection. This can be demonstrated by opening a small window near the roof of a greenhouse; the temperature drops considerably. This principle is the basis of the autovent automatic cooling system. Thus, the glass used for a greenhouse works as a barrier to air flow, and its effect is to trap energy within the greenhouse. The air that is warmed near the ground is prevented from rising indefinitely and flowing away.

Although heat loss due to thermal conduction through the glass and other building materials occurs, net energy (and therefore temperature) increases inside the greenhouse.

Convection
Convection is the concerted, collective movement of ensembles of molecules within fluids (e.g., liquids, gases) and rheids. It is the circulatory motion that occurs in a fluid at a nonuniform temperature owing to the variation of its density and the action of gravity.

Blackbody
A blackbody is an idealized physical body that absorbs all incident electromagnetic radiation, regardless of frequency or angle of incidence.

Real materials emit energy at a fraction ‒ called the emissivity ‒ blackbody energy levels. By definition, a blackbody in thermal equilibrium has an emissivity of ε = 1.0. A source with lower emissivity independent of frequency often is referred to as a gray body. Construction of blackbodies with emissivity as close to one as possible remains a topic of current interest. A white body is one with a "rough surface that reflects all incident rays completely and uniformly in all directions."

Effective temperature
The effective temperature of a body such as a star or planet is the temperature of a blackbody that would emit the same total amount of electromagnetic radiation. Effective temperature is often used as an estimate of a body's temperature when the body's emissivity curve (as a function of wavelength) is not known.

When the star's or planet's net emissivity in the relevant wavelength band is less than unity (less than that of a blackbody), the actual temperature of the body will be higher than the effective temperature. The net emissivity may be low due to surface or atmospheric properties, including the greenhouse effect.

Emissivity
The emissivity of the material (usually written ε or e) is the relative ability of its surface to emit energy by radiation. It is the ratio of energy radiated by a particular material to energy radiated by a blackbody at the same temperature. A true blackbody would have an ε = 1 while any real object would have ε < 1. Emissivity is a dimensionless quantity.

In general, the duller and blacker a material is, the closer its emissivity is to 1. The more reflective a material is, the lower its emissivity. Highly polished silver has an emissivity of about 0.02.

Sources:

http://en.wikipedia.org/wiki/Greenhouse_effect
http://en.wikipedia.org/wiki/Greenhouse_gas
http://en.wikipedia.org/wiki/Greenhouse
http://en.wikipedia.org/wiki/Convection
http://en.wikipedia.org/wiki/Blackbody
http://en.wikipedia.org/wiki/Effective_temperature
http://en.wikipedia.org/wiki/Emissivity

Sunday, May 12, 2013

antibiotic

An antibacterial is an agent that inhibits bacterial growth or kills bacteria. The term is often used synonymously with the term antibiotic(s). Today, however, with increased knowledge of the causative agents of various infectious diseases, antibiotic(s) has come to denote a broader range of antimicrobial compounds, including anti-fungal and other compounds.

The term antibiotic was first used in 1942 by Selman Waksman and his collaborators in journal articles to describe any substance produced by a microorganism that is antagonistic to the growth of other microorganisms in high dilution. This definition excluded substances that kill bacteria, but are not produced by microorganisms (such as gastric juices and hydrogen peroxide). It also excluded synthetic antibacterial compounds such as the sulfonamides. Many antibacterial compounds are relatively small molecules with a molecular weight of less than 2000 atomic units.

With advances in medicinal chemistry, most of today's antibacterials chemically are semisynthetic modifications of various natural compounds. Compounds that are still isolated from living organisms are the aminoglycosides, whereas other antibacterials -- for example, the sulfonamides, the quinolones, and the oxazolidinones -- are produced solely by chemical synthesis. In accordance with this, many antibacterial compounds are classified on the basis of chemical/biosynthetic origin into natural, semisynthetic, and synthetic. Another classification system is based on biological activity; in this classification, antibacterials are divided into two broad groups according to their biological effect on microorganisms: bactericidal agents kill bacteria, and bacteriostatic agents slow down or stall bacterial growth.

Antibiotic resistance is a form of drug resistance whereby some (or, less commonly, all) sub-populations of a microorganism, is usually a bacterial species, are able to survive after exposure to one or more antibiotics; pathogens resistant to multiple antibiotics are considered multidrug resistant (MDR) or, more colloquially, superbugs.

Antibiotic resistance is a serious and growing phenomenon in contemporary medicine and has emerged as one of the pre-eminent public health concerns of the 21st century, particularly as it pertains to pathogenic organisms (the term is especially relevant to organisms which cause disease in humans). In the simplest cases, drug-resistant organisms may have acquired resistance to first-line antibiotics, thereby necessitating the use of second-line agents. Typically, a first-line agent is selected on the basis of several factors including safety, availability and cost; a second-line agent is usually broader in spectrum, has a less favorable risk-benefit profile and is more expensive or, in dire circumstances, is locally unavailable.

It may take the form of a spontaneous or induced genetic mutation, or the acquisition of resistance genes from other bacterial species by horizontal gene transfer via conjugation, transduction, or transformation. Many antibiotic resistance genes reside on transmissible plasmids, facilitating their transfer. Exposure to an antibiotic naturally selects for the survival of the organisms with the genes for resistance. In this way, a gene for antibiotic resistance may readily spread through an ecosystem of bacteria. Antibiotic-resistance plasmids frequently contain genes conferring resistance to several different antibiotics.

Genes for resistance to antibiotics, like the antibiotics themselves, are ancient. However, the increasing prevalence of antibiotic-resistant bacterial infections seen in clinical practice stems from antibiotic use both within human medicine and veterinary medicine. Any use of antibiotics can increase selective pressure in a population of bacteria to allow the resistant bacteria to thrive and the susceptible bacteria to die off. As resistance towards antibiotics becomes more common, a greater need for alternative treatments arises. However, despite a push for new antibiotic therapies there has been a continued decline in the number of newly approved drugs. Antibiotic resistance therefore poses a significant problem.

Plasmid
A plasmid is a small DNA molecule that is physically separate from, and can replicate independently of, chromosomal DNA within a cell. Most commonly found as small circular, double stranded DNA molecules in bacteria, plasmids are sometimes present in archaea and eukaryotic organisms. In nature, plasmids carry genes that may benefit survival of the organism (e.g. antibiotic resistance), and can frequently be transmitted from one bacterium to another (even of another species) via horizontal gene transfer.

Plasmid sizes vary from 1 to 1000 kilo base pairs (kbp). The number of identical plasmids in a single cell can range anywhere from one to thousands under some circumstances. Plasmids can be considered part of the mobilome because they are often associated with conjugation, a mechanism of horizontal gene transfer.

Plasmid host-to-host transfer requires direct mechanical transfer by conjugation, or changes in incipient host gene expression allowing the intentional uptake of the genetic element by transformation. Plasmids provide a mechanism for horizontal gene transfer within a population of microbes and typically provide a selective advantage under a given environmental state. Plasmids may carry genes that provide resistance to naturally occurring antibiotics in a competitive environmental niche, or the proteins produced may act as toxins under similar circumstances.

Sources:

http://en.wikipedia.org/wiki/Antibacterial
http://en.wikipedia.org/wiki/Antibiotic_resistance
http://en.wikipedia.org/wiki/Plasmid